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Neuroplasticity: The Revolution in Neuroscience and Psychology, Part I

For decades neuroscientific dogma held that the brain was immutable, unchangeable and static. New research in the field of neuroscience has shown this core belief to be untrue, and revealed that the brain is in fact a dynamic organ that changes almost constantly.

The majority of the ‘fundamentals' that we learned in Psych 101 are wrong. Memory maps (remember the Homunculus?) not only differ widely from individual to individual, but they can change radically in the same individual over a matter of days. The brain is not hardwired, but plastic. Dendritic and synaptic connections have been demonstrated to rewire themselves via experience, and, most intriguingly, through mind training. The implications of these findings for neuroscience, cognitive science and applied psychology are staggering.

One of the most fascinating aspects of this revolution in neuroscientific study is that it has been motivated in no small part by a simple Tibetan monk named Tenzin Gyatso -- more commonly known as His Holiness The Dalai Lama. The Dalai Lama has long had an interest in science and holds that, if Buddhist doctrine can be challenged or even disproved by science, then it should. He, himself, was the first to do this when, as a young man, he discovered that the Buddhist teachings on astronomy were in error. It is Buddhism that is bridging the gap between science and spirituality.

In 2004 the first in a series of now annual collaborative conferences between The Dalai Lama and various scientists, philosophers and researchers, organized by Francesco Varela and Adam Engel, was convened at Dharamsala. It was called the Mind and Life Institute. The intent of the conference was to investigate the relationship between neuroscience and Buddhist teachings.

The course and content of these discourses has been elegantly documented by Newsweek science writer Sharon Begley in her book Train Your Mind, Change Your Brain. In her book, Begley lays out for us how, at the end of the 19th century, the scientific community held the position that the brain was changeable, how that position was reversed and became concretized (no pun intended) and how, until only recently, research demonstrating this gross doctrinal error in neuroscience has been largely ignored, if not scorned, by the scientific community.

She then goes on to discuss how the Mind and Life collaborations have become a microcosmic distillation of this revolution in the field of neuroscience, and how researchers have accessed an extensive population of Buddhist monks and practitioners, highly adept at meditation and mind control techniques, to demonstrate how thought can, quite literally, change the brain.

What does that mean for us? It means that cultivation theory, which suggests that repeated exposure to social messages shapes belief systems, not only has a demonstrable biological correlate, but that changing our perception of those social messages can not only change our thinking, but change the way we synaptically process the message -- permanently.

It means that social constructionism and the social construction of reality is not only a two-way street, but a genuine collaboration between self and society. We literally do create our reality, and we can change it, just as it can change us. More to the point, we really, literally and demonstrably can change as people.

It means that with proper mind training - rigorous and intensive training, this is not a magic bullet - it may be possible to actually think our way out of depression or OCD, or retrain the cognitive processing mechanism to turn dyslexia into fluid reading skills.

It means that collaborative talk therapy, by changing perceptions and perspective, can change the brain, which changes thinking and, by association, behavior - for real. Is this not, in fact, what Cognitive Behavioral Therapy (CBT) and Dialectic Behavioral Therapy (DBT) -- which, by the way, is considerably influenced by Marsha Linehan's 20+ years as a Buddhist meditator -- already actually do?

It means that addicts may not really be addicts for life (forgoing, of course, the biological component potentially associated with alcoholism), and sufferers of Borderline Personality Disorder may not be enslaved by the throes of emotional dysregulation forever and ever.

It even means that all that New Age gobble-dee-gook about positive affirmations and positive thinking changing how you feel about yourself and your world might actually have some basis in hard science.

More to the point, it means that we, as professionals, need to rethink whether or not we can continue to think of psychology as a "soft" science, and must start to re-envision what we do in our role as social change agents as having a demonstrable, biological correlate.

Do I sound excited? I am. When I was first introduced to the idea of neuroplasticity, I thought it was interesting. The more I learn about the subject, the more I realize that we are on a frontier. There is a familiarity to all of it, and, at the same time, my entire intellectual perspective has been turned on its head - possibly even dropped on its head.

This is Part I of a series - we will get to the hard facts, the science, the references and such in later posts. Too much too soon is more than a brain - my brain, anyway -- can handle.

© 2008 Michael J. Formica, All Rights Reserved

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Comments

Thanks for this fantastic blog!

Dear Michael,
I just wanted to take a minute to thank you for initiating and keeping up with this fantastic blog. Every morning I put conference calls and spread sheets on hold and take a few minutes to feed my brain and soul by reading your posts. I discovered this treasure a few weeks ago in a moment when I was looking for answers to deal with a very unsettling personal situation. Since then I have found a place to come for wisdom and reassurance. Articles that have been very helpful are “Living in Fear Vs Living in Certainty” and “Social Intelligence, Authentic Relationship and Conscious Communication”.
Keep up the good work… one mind at the time!


Thank you

Dear Raquel:

Thank you for your too kind words, I truly appreciate them.

It has been a tremendous opportunity for me to find a forum in which to share these simple thoughts and ideas that were once confined to the consulting room, individual conversations and my own head. If they hold some meaning for those who come across them, so much better.

I hope you have gathered some solace regards your own situation. And if you find yourself confronting anything that you feel you may wish to address more directly, do not hesitate to contact me.

Blessings and namaste,
Michael


responsibility

I have been very excited about brain plasticity for some time and it seems as if there is finally a mass movement towards recognizing the powerful control we may exert over our own conciousness. The idea is that of a top down relationship vs. a bottom up relationship and it gives much more respect to the awareness we all feel as humans even when told we are just complex machines. I am anxious to see how this change of view may effect public policy. Will people be held more responsible for actions carried out with a "disturbed mind?" Moral relativism won't hold up in the face of willfull, concious acts relsulting in measurable physical change.


Neuroplasticity and Autism

Michael, another great blog post. I really enjoy reading your perspective.

It's interesting because one of the arguments for "early intervention" for kids with Autism is that we need to get them a quality education in early childhood, while the brain is still forming and making connections. Although this is changing somewhat, the view is often that this time period (up through the age of about 5 years) is some sort of window that will be closed, after which significant improvements are less likely to be made.

I'm certainly interested in hearing more about this...it may help get additional funding for services other than life skills training for older students with Autism who are past the "early intervention" window.

Have a lovely day,

Nicole Caldwell, M.Ed.
http://blogs.psychologytoday.com/blog/positively-autism
http://www.PositivelyAutism.com/


Thanks, Nicole...

Nicole:

Thank you so much for your kind words. This is a very exciting field -- it's be interesting to see where it leads us, as both social scientists and educators.

Blessings,
Michael


Thanks, Nicole...

Nicole:

Thank you so much for your kind words. This is a very exciting field -- it'll be interesting to see where it leads us, both as social scientists and educators.

Blessings,
Michael


Neuroplasticiy, Emotional Resonance, Compassion

This post is in response to Michael Formica’s article on Psychology Today Blog where he speaks of the recent developments of brain science and neuroplasticity; namely, "Dendritic and synaptic connections have been demonstrated to rewire themselves via experience, and, most intriguingly, through mind training. The implications of these findings for neuroscience, cognitive science and applied psychology are staggering."

And Michael while I do not question your contention that mind training plays a most intriguing role in rewiring the brain, I have found that experiences in meditation (mindfulness development) combined with relational exchanges where emotional resonance occurs makes for the most substantial changes in the brain. And I must say that I am less knowledgeable about Cognitive Behavioral Therapy. If you could fill me in on CBT and its significance, I would be indebted to you.

My experience lies mostly in the emotional realms where both client and therapist experience deep, core emotions and then share that experience in the session and both "feel felt" by the other. This emotional resonance occurs when emotional states converge and the two people share in the experience of the other. This also occurs when we read of a tragic war death and are moved to emotion by what we imagine the family must be experiencing.

In Daniel Siegel’s most recent work, The Mindful Brain, he speaks, like Michael does, to the significance of meditation and mindfulness. He also goes further and speaks to the concept of Mirror Neurons. And Sue Johnson in Hold Me Tight identifies these "nerve cells that activate in sympathy and in the same brain location as the nerve cells of the person whose actions we are watching. ..These neurons help us sense what others intend and help us connect with what the other feels…Scientists suggest that the more active a person’s mirror neuron system, the stronger his or her empathy will be."

This empathy is what Buddhists refer to as Compassion. Meditating alone in a cave or in isolation can bring about changes in our caring or compassion for others.And the resonance along with the mindfulness allows for a greater capacity for Compassion.

I won’t take the time right now to discuss Oxytocin but this is the neurotransmitter which is probably most relevant in the rewiring and the changes that take place in the brain.

In our just released book on Amazon, In a Cradle of Words: Intimate Encounters in Relational Therapy, my co-author Laurel Vogel reveals her personal story mostly around her father’s death and there is an interplay between her pain, the creation of new neural pathways using Relational Therapy, and her healing.


Mind training is meditation

Christopher:

Mind training is meditation, as meditation is not simply about sitting.

You may be interested in exploring some of the more scientific, evidence-based works on the subject of neuroplasticity, specifically those related to the work being done in tandem with the Mind and Life Institute, as well as that done by Daniel Goleman and others.

Regards your reference to Oxytocin, while there is evidence to suggest that this neurotransmitter does play a role in autonomic and reflexive behavior, there is none to suggest that it has been demonstrated to play a role in neural restructuring.

Regards,
Michael


Mind Life Institute

Michael,
Thanks for the suggestion. I will check out the Mind and Life Institute. And while the scientific verification is important, the real life personal experience as a client and a therapist for me is the most significant.

Christopher


Daniel Siegel research

Michael,
Your suggestion that I explore "more scientific, evidence-based works on the subject of neuroplasticity" implies that Daniel Siegel's work is not scientific evidence-based. I have not checked on his research and have only taken him on his word that he has done the research to verify the validity of "Mirroring Neurons" and "Emotional resonance".

I have not done research and I KNOW from experience that these are valid. It is the same with the Oxytocin where I have experienced the effects of this hormone/neurotransmitter in myself and my clients and its healing properties. I have seen and felt it counteract cortisol in the blink of an eye, and take a person from great distress to relaxed and relieved and connected.

Have you had that experience? Or witnessed it?

Christopher


Research

Chris:

No disrespect intended. My background is as a research scientist first, clinician second.

As far as I'm concerned, unless someone can show me hard numbers, it's just a conversation -- based on anecdotal information.

Experience is not research, it is experience. That one could make the leap from "feeling better through experience" to the notion that oxytocin is the neurotransmitter for that change without blood work, CAT scans, PET scans and/or MRIs is just bad science.

Lifting weights and running influences depression...I could say that's oxytocin, too. Except there is demonstrable evidence to show it's endorphins and serotonin.

As Reagan, and Teddy Roosevelt before him, said, "Trust, with verification."

Again, all due respect, but, never take anyone at their word.

Blessings,
Michael


Daniel Siegel

Michael
Thanks for your respectful response. I appreciate that. I know that scientists need cold hard facts. Are you familiar with Dr Siegel's research and book, The Mindful Brain? Dr Allan Schore? Dr Bessel van der Kolk?

I believe these experts in the field of Trauma and the Brain have done research. Siegel, using Pet Scans and MRI's, has research that verifies "Mirror Neurons" and "Emotional Resonance" exist and that they seriously impact the therapeutic relationship. It does not verify Oxytocin but I believe it does show changes to the amygdala.

And yes my proof is anecdotal and I KNOW that this relational therapy works.

Christopher


The Research Needs to Be there to Back up the Claims

Neuroplasticity and Neurogenesis and hot topics, and they show us lots of encouraging ideas. I just think it gets out of hand when writers start claiming what the research doesn't say (not that this article does). For instance, I just did a review for the book "A brilliant mind" where the author claims one could drastically increase their IQ by memorizing vocab words. There's just no evidence!


The research by Daniel

The research by Daniel Siegel has been done. Here is a brief writeup on an internet site:

"Neuronal circuits are wired through a combination of nature and nurture, genetics and experience. The kind of parenting we receive as children, the nature of our relationships throughout life, the experience of therapy, all change the brain by changing synaptic connections and circuits. “Human connections create neuronal connections” (Siegel, 1999, p. 85). Because of the impact social relationships have on our brains, Siegel has suggested that “the brain is the social organ of the body” (Siegel & Hartzell, 2003, p. 97). It is clear from neuroscience that nature and nurture are mutually recursive. “Experience shapes the brain throughout life by altering the connections among neurons….Experience is biology” (Siegel & Hartzell, 2003, pp. 33-34). These observations are not mere metaphors; they are based on extensive and compelling research on the human brain, development, and relationships. Beyond affecting synaptic connections, experience—especially early parent-child experience—can modify the actual activity of genes (Begley, 2007)".

I have clearly "experienced" how my experiences of emotional resonance have altered my neural pathways so that I now have substantially different experiences than I had before. I discovered this on my own without science and now science has validated my experience. If science had never made these discoveries my experience would be no less valid. I think that is the problem with only "believing" scientific based evidence. This of course does not give us freedom to make claims like "memorizing vocabulary words raises IQ".

www.relationalcounselingseattle.com/blog/

Christopher


Because I said so...

Regrettably, Chris, the "because I said so" argument is what keeps psychology at the fringes of science. It is what keeps us "just psychologists".

While I do not doubt your personal experience, without documented evidence, it is just experience.

As for the work you cite, I am certain that it provides substantive evidence for your contentions, and I am anxious to add those volumes to my library.

Regards,
Michael


This is an extremely

This is an extremely interesting post. I do think that the "mind over matter" mentality has a lot of fruit to bear. What needs to be done now is a detailed examination of the synaptic and dendritic changes that occur in the brain. You may want to check this site out: http://www.nytimes.com/2007/03/11/magazine/11Neurolaw.t.html?_r=1&scp=7&...


Thanks for the heads up...

It's printing as we speak -- I'll take a look. The review you suggest might meet with a bit of a yawn in this forum, but what you say is quite correct.

Blessings,
Michael


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